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醫(yī)學(xué)樣稿翻譯是新語(yǔ)絲北京翻譯公司擅長(zhǎng)領(lǐng)域，以下就是我公司專(zhuān)業(yè)醫(yī)學(xué)翻譯譯員翻譯整理的樣稿。
CHF is a debilitating disease currently afflicting almost 5 million people in the USA with approximately 550,000 new cases diagnosed each year.2 In the USA, it is the most rapidly growing cardiovascular disease and it has been estimated that approximately 20 million more Americans may have asymptomatic cardiac impairment.3
翻譯：CHF是一種致衰弱疾病，目前美國(guó)有將近500萬(wàn)人患有此病，每年診斷出的新發(fā)病例約為55萬(wàn)人。2在美國(guó)，這是一種增長(zhǎng)最為快速的心血管疾病，預(yù)計(jì)約有2000多萬(wàn)美國(guó)人出現(xiàn)無(wú)癥狀心臟受損。3
The class of cardiac neurohormones was first described by de Bold et al.4,5 This family of structurally similar but genetically distinct molecules includes BNP, atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP). These three natriuretic peptides (NPs) are synthesized as high molecular weight precursors. NT-proBNP is a cleavage product of pro-Brain natriuretic peptide (proBNP) The precursor molecule proBNP is a peptide consisting of 108 amino acids .6,7 During intracellular peptide maturation, cleavage of this precursor molecule by an endoproteinase results in formation of the biologically active BNP peptide and the biologically inactive 76 amino acid N-terminal fragment, NT-proBNP. 8
翻譯：de Bold等人最先描述了心臟神經(jīng)激素的類(lèi)別。4,5這一系列在結(jié)構(gòu)上相似，但分子基因明顯不同，其中包括BNP、心房鈉尿肽（ANP）和C型鈉尿肽（CNP）。這三種尿鈉肽合成為高分子量前體。NT-proBNP是腦鈉肽原（proBNP）的一種分裂產(chǎn)物。前體分子proBNP是一種由108種氨基酸構(gòu)成的肽。6,7在細(xì)胞內(nèi)肽成熟期間，由內(nèi)切蛋白酶引起的該前體分子的分裂導(dǎo)致具有生物活性的BNP肽和76氨基酸氨基末端片段,NT-proBNP的形成。8
The NPs possess potent diuretic, natriuretic and vasodilatory properties and have been reported as valuable diagnostic and prognostic markers in cardiovascular disease, particularly for patients in NYHA classes I-IV CHF.9 In particular, measurement of plasma concentrations of NT-proBNP has utility as a valuable tool for aiding in the diagnosis and the assessment of severity of patients with CHF.10,11
翻譯：NPs含有有效利尿劑、排鈉利尿和血管舒張物質(zhì)，現(xiàn)已報(bào)告為一種有用的心血管疾病診斷和預(yù)后標(biāo)志物，尤其是對(duì)于NYHA I-IV級(jí) CHF患者。9特別是，在診斷和評(píng)價(jià)CHF患者的嚴(yán)重性方面， NT-proBNP血漿濃度測(cè)量可作為一種輔助工具使用。10,11
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